TY - JOUR
T1 - An EULAR study group pilot study on reliability of simple capillaroscopic definitions to describe capillary morphology in rheumatic diseases
AU - on behalf of the EULAR study group on microcirculation
AU - Smith, Vanessa
AU - Beeckman, Sam
AU - Herrick, Ariane L.
AU - Decuman, Saskia
AU - Deschepper, Ellen
AU - De Keyser, Filip
AU - Distler, Oliver
AU - Foeldvari, Ivan
AU - Ingegnoli, Francesca
AU - Müller-Ladner, Ulf
AU - Riccieri, Valeria
AU - Riemekasten, Gabriela
AU - Sulli, Alberto
AU - Voskuyl, Alexandre
AU - Cutolo, Maurizio
AU - Abdessemed, Amina
AU - Adriano, Alatri
AU - Allanore, Yannick
AU - Andreoli, Laura
AU - Araújo, Filipe
AU - Barth, Zoltán
AU - Brasseur, Jean Pierre
AU - Campochiaro, Corrado
AU - Blan, Rayma Castalia Peña
AU - Chartrand, Sandra
AU - Corvaglia, Stefania
AU - Cuciti, Cristina
AU - Damjanov, Nemanja
AU - De Almeida Borges, Fernando
AU - De Keyser, Eline
AU - De Knop, Kathleen
AU - De Kock, Joris
AU - Fernandez, Maria Jose
AU - Filippini, Matteo
AU - Garcia, Ana Cunha Luiza
AU - Kwan, Carmen Ho Tze
AU - Hermann, Walter
AU - Pichardo, Sonia Houston
AU - Ickinger, Claudia
AU - Ikic, Alena
AU - Kopec-Medrek, Magdalena
AU - Kubo, Satoshi
AU - Makol, Ashima
AU - Marrazza, Mariagrazia
AU - Mesa, Miguel Antonio
AU - Michalska-Jakubus, Małgorzata
AU - Miossi, Renata
AU - Mogosan, Corina
AU - Moretti, Giovanna
AU - Franco, Carlos Jaime Velasquez
N1 - Publisher Copyright:
© The Author 2015.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Objective: To propose simple capillaroscopic definitions for interpretation of capillaroscopic morphologies and to assess inter-rater reliability.Methods: The simple definitions proposed were: normal--hairpin, tortuous or crossing; abnormal--not hairpin, not tortuous and not crossing; not evaluable--whenever rater undecided between normal and abnormal. Based upon an aimed kappa of 0.80 and default prevalences of normal (0.4), abnormal (0.4) and not evaluable (0.2) capillaries, 90 single capillaries were presented to three groups of raters: experienced independent raters, n = 5; attendees of the sixth EULAR capillaroscopy course, n = 34; novices after a 1-h course, n = 11. Inter-rater agreement was assessed by calculation of proportion of agreement and by kappa coefficients.Results: Mean kappa based on 90 capillaries was 0.47 (95% CI: 0.39, 0.54) for expert raters, 0.40 (95% CI: 0.36, 0.44) for attendees and 0.46 (95% CI: 0.41, 0.52) for novices, with overall agreements of 67% (95% CI: 63, 71), 63% (95% CI: 60, 65) and 67% (95% CI: 63, 70), respectively. Comparing only normal vs the combined groups of abnormal and not evaluable capillaries did increase the kappa: 0.51 (95% CI: 0.37 ,: 0.65), 0.53 (95% CI: 0.49, 0.58) and 0.55 (95% CI: 0.49, 0.62). On the condition that the capillaries were classifiable, the mean kappa was 0.62 (95% CI: 0.50, 0.74) for expert raters (n = 65), 0.76 (95% CI: 0.69, 0.83) for attendees (n = 20) and 0.81 (95% CI: 0.74, 0.89) for novices (n = 44).
AB - Objective: To propose simple capillaroscopic definitions for interpretation of capillaroscopic morphologies and to assess inter-rater reliability.Methods: The simple definitions proposed were: normal--hairpin, tortuous or crossing; abnormal--not hairpin, not tortuous and not crossing; not evaluable--whenever rater undecided between normal and abnormal. Based upon an aimed kappa of 0.80 and default prevalences of normal (0.4), abnormal (0.4) and not evaluable (0.2) capillaries, 90 single capillaries were presented to three groups of raters: experienced independent raters, n = 5; attendees of the sixth EULAR capillaroscopy course, n = 34; novices after a 1-h course, n = 11. Inter-rater agreement was assessed by calculation of proportion of agreement and by kappa coefficients.Results: Mean kappa based on 90 capillaries was 0.47 (95% CI: 0.39, 0.54) for expert raters, 0.40 (95% CI: 0.36, 0.44) for attendees and 0.46 (95% CI: 0.41, 0.52) for novices, with overall agreements of 67% (95% CI: 63, 71), 63% (95% CI: 60, 65) and 67% (95% CI: 63, 70), respectively. Comparing only normal vs the combined groups of abnormal and not evaluable capillaries did increase the kappa: 0.51 (95% CI: 0.37 ,: 0.65), 0.53 (95% CI: 0.49, 0.58) and 0.55 (95% CI: 0.49, 0.62). On the condition that the capillaries were classifiable, the mean kappa was 0.62 (95% CI: 0.50, 0.74) for expert raters (n = 65), 0.76 (95% CI: 0.69, 0.83) for attendees (n = 20) and 0.81 (95% CI: 0.74, 0.89) for novices (n = 44).
KW - Capillaroscopy
KW - Definitions
KW - EULAR study group on microcirculation
KW - Experts
KW - Morphology
KW - Novices
KW - Reliability
KW - Trainees
UR - http://www.scopus.com/inward/record.url?scp=84965076035&partnerID=8YFLogxK
UR - https://pubmed.ncbi.nlm.nih.gov/26843483/
U2 - 10.1093/rheumatology/kev441
DO - 10.1093/rheumatology/kev441
M3 - Artículo en revista científica indexada
C2 - 26843483
AN - SCOPUS:84965076035
SN - 1462-0324
VL - 55
SP - 883
EP - 890
JO - Rheumatology
JF - Rheumatology
IS - 5
ER -