Latin America and other places in the world have tropical regions, from which multiple diseases emerge. Cutaneous Leishmaniasis (CL) is one of the most common pathologies that attack the populations on these areas, generating an ulcer and leaving marks for life. The difficult access to appropriate medical attention of affected populations raises the need for new instruments and techniques that facilitate the diagnosis and monitoring of treatments for this disease. This article proposes a methodology of analysis of golden hamster skin with cutaneous ulcer caused by leishmaniasis through a three-layer inverse reflectance model, genetic algorithms and the Hyperspectral image acquisition system ASCLEPIOS. As a result, the concentration maps of: thickness of the epidermis (epi), epidermis plus thickness of the dermis (epiPder), volumetric fraction of blood (Fblood), diameter of the Collagen particles (Coll), volumetric fraction of collagen (Fcoll), diameter of the Fibroblast particles (Fibro), volumetric fraction of melanin (Fmel), diameter of Keratynocytes particles (Kera), diameter of Macrophages particles (Macro), and oxygen saturation (OS) were obtained.
|Title of host publication||15th International Symposium on Medical Information Processing and Analysis|
|Editors||Eduardo Romero, Natasha Lepore, Jorge Brieva|
|State||Published - 2020|
|Event||15th International Symposium on Medical Information Processing and Analysis, SIPAIM 2019 - Medellin, Colombia|
Duration: 6 Nov 2019 → 8 Nov 2019
|Name||Proceedings of SPIE - The International Society for Optical Engineering|
|Conference||15th International Symposium on Medical Information Processing and Analysis, SIPAIM 2019|
|Period||6/11/19 → 8/11/19|
Bibliographical noteFunding Information:
The authors would like to acknowledge the financial support given by Departamento Administrativo de Ciencia y tecnologia de Colombia - COLCIENCIAS-, Instituto Tecnológico Metropolitano, Universidad de Antioquia, Universidad Pontificia Bolivariana, and Kinetics Systems S.A.S (Medellín-Colombia), under the project number 57186.
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- Concentration maps
- Genetic algorithms
- Golden hamster