Analysis of cutaneous leishmaniasis hyperspectral images by means of an inverse modeling procedure

Deivid Botina-Monsalve, July Galeano, Maria C. Torres-Madronero, Artur Zarzycki, Johnson Garzón, Javier Murillo, Sara M. Robledo, Franck Marzani

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    Abstract

    Latin America and other places in the world have tropical regions, from which multiple diseases emerge. Cutaneous Leishmaniasis (CL) is one of the most common pathologies that attack the populations on these areas, generating an ulcer and leaving marks for life. The difficult access to appropriate medical attention of affected populations raises the need for new instruments and techniques that facilitate the diagnosis and monitoring of treatments for this disease. This article proposes a methodology of analysis of golden hamster skin with cutaneous ulcer caused by leishmaniasis through a three-layer inverse reflectance model, genetic algorithms and the Hyperspectral image acquisition system ASCLEPIOS. As a result, the concentration maps of: thickness of the epidermis (epi), epidermis plus thickness of the dermis (epiPder), volumetric fraction of blood (Fblood), diameter of the Collagen particles (Coll), volumetric fraction of collagen (Fcoll), diameter of the Fibroblast particles (Fibro), volumetric fraction of melanin (Fmel), diameter of Keratynocytes particles (Kera), diameter of Macrophages particles (Macro), and oxygen saturation (OS) were obtained.

    Original languageEnglish
    Title of host publication15th International Symposium on Medical Information Processing and Analysis
    EditorsEduardo Romero, Natasha Lepore, Jorge Brieva
    PublisherSPIE
    ISBN (Electronic)9781510634275
    DOIs
    StatePublished - 2020
    Event15th International Symposium on Medical Information Processing and Analysis, SIPAIM 2019 - Medellin, Colombia
    Duration: 6 Nov 20198 Nov 2019

    Publication series

    NameProceedings of SPIE - The International Society for Optical Engineering
    Volume11330
    ISSN (Print)0277-786X
    ISSN (Electronic)1996-756X

    Conference

    Conference15th International Symposium on Medical Information Processing and Analysis, SIPAIM 2019
    Country/TerritoryColombia
    CityMedellin
    Period6/11/198/11/19

    Bibliographical note

    Funding Information:
    The authors would like to acknowledge the financial support given by Departamento Administrativo de Ciencia y tecnologia de Colombia - COLCIENCIAS-, Instituto Tecnológico Metropolitano, Universidad de Antioquia, Universidad Pontificia Bolivariana, and Kinetics Systems S.A.S (Medellín-Colombia), under the project number 57186.

    Publisher Copyright:
    © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

    Keywords

    • ASCLEPIOS
    • Concentration maps
    • Genetic algorithms
    • Golden hamster
    • Leishmaniasis

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