TY - JOUR
T1 - Association between major depression and arterial hypertension in a Colombian population
AU - Collazos-Perdomo, D.
AU - Ramirez-Ramos, C. F.
AU - Torres de Galvis, M. Y.
AU - Correas-Orozco, L.
AU - Ramirez-Mendez, D.
AU - Castilla Agudelo, G. A.
AU - Martinez Cano, C. A.
AU - Gallego, C.
AU - Saldarriaga, C.
PY - 2020/1
Y1 - 2020/1
N2 - Introduction: A third of hypertensive patients have major depression, a relationship that is associated with a worse prognosis. The objective of the study was to estimate the association between depression and high blood pressure, as well as to establish the possible bidirectionality of the conditions. Materials and methods: Retrospective cohort study. People between 18 and 65 years old with high blood pressure, depression or use of medications for their management were included. To analyze the antecedent, a comorbidity model was performed. A bivariate analysis was performed and then a multivariate logistic regression. The association was estimated using the Chi-square test and the odds ratios that were crude and adjusted to the other variables included in the analysis. The Hosmer-Lemeshow test was used to assess the goodness of fit. SPSS® v.21 was used as the statistical package. Results: A total of 1,721 people were included in the study. The prevalence of depression in patients with and without hypertension was 17.4 and 12.6%, respectively, with a 43% risk of hypertension in people with depression. In patients with depression, it preceded the diagnosis of hypertension in 64.8% of cases and in hypertensive patients, 22.2% were later diagnosed with depression. The association between high blood pressure and major depression remained significant after adjusting for the other risk factors. Conclusions: Depression was found as a risk factor for high blood pressure, with a 2-way risk relationship between depression and high blood pressure.
AB - Introduction: A third of hypertensive patients have major depression, a relationship that is associated with a worse prognosis. The objective of the study was to estimate the association between depression and high blood pressure, as well as to establish the possible bidirectionality of the conditions. Materials and methods: Retrospective cohort study. People between 18 and 65 years old with high blood pressure, depression or use of medications for their management were included. To analyze the antecedent, a comorbidity model was performed. A bivariate analysis was performed and then a multivariate logistic regression. The association was estimated using the Chi-square test and the odds ratios that were crude and adjusted to the other variables included in the analysis. The Hosmer-Lemeshow test was used to assess the goodness of fit. SPSS® v.21 was used as the statistical package. Results: A total of 1,721 people were included in the study. The prevalence of depression in patients with and without hypertension was 17.4 and 12.6%, respectively, with a 43% risk of hypertension in people with depression. In patients with depression, it preceded the diagnosis of hypertension in 64.8% of cases and in hypertensive patients, 22.2% were later diagnosed with depression. The association between high blood pressure and major depression remained significant after adjusting for the other risk factors. Conclusions: Depression was found as a risk factor for high blood pressure, with a 2-way risk relationship between depression and high blood pressure.
KW - Adherence
KW - Depression
KW - Hypertension
KW - Treatment
UR - https://www.mendeley.com/catalogue/3d00d952-493f-3289-b0d8-a8e6dfb8d38d/
U2 - 10.1016/j.hipert.2020.06.002
DO - 10.1016/j.hipert.2020.06.002
M3 - Artículo en revista científica indexada
C2 - 32675035
SN - 1889-1837
VL - 37
SP - 162
EP - 168
JO - Hipertension y Riesgo Vascular
JF - Hipertension y Riesgo Vascular
IS - 4
ER -