TY - JOUR
T1 - Bovine leukemia virus detection in humans
T2 - A systematic review and meta-analysis
AU - Mendoza, Willington
AU - Isaza, Juan Pablo
AU - López, Lucelly
AU - López-Herrera, Albeiro
AU - Gutiérrez, Lina A.
N1 - Publisher Copyright:
© 2023
PY - 2023/10/2
Y1 - 2023/10/2
N2 - To review the available studies on the frequency of detection of the bovine leukemia virus in human samples, a systematic review with meta-analysis of the scientific literature was carried out, including papers published in English, Spanish, and Portuguese in 5 multidisciplinary databases. We collected information from different populations following a detailed and reproducible search protocol in which two researchers verified the inclusion and exclusion criteria. We identified 759 articles, of which only 33 met the inclusion criteria. Analyzed studies reported that the presence of the virus was measured in human samples, such as paraffin-embedded breast tissue and peripheral blood from 10,398 individuals, through serological and molecular techniques. An overall virus frequency of 27% (Ranging between 17 and 37%) was observed, with a high-frequency data heterogeneity between studies. The presence of this virus in different human biological samples suggests the need to investigate further its transmission route to humans and its potential role in developing and progressing diseases.
AB - To review the available studies on the frequency of detection of the bovine leukemia virus in human samples, a systematic review with meta-analysis of the scientific literature was carried out, including papers published in English, Spanish, and Portuguese in 5 multidisciplinary databases. We collected information from different populations following a detailed and reproducible search protocol in which two researchers verified the inclusion and exclusion criteria. We identified 759 articles, of which only 33 met the inclusion criteria. Analyzed studies reported that the presence of the virus was measured in human samples, such as paraffin-embedded breast tissue and peripheral blood from 10,398 individuals, through serological and molecular techniques. An overall virus frequency of 27% (Ranging between 17 and 37%) was observed, with a high-frequency data heterogeneity between studies. The presence of this virus in different human biological samples suggests the need to investigate further its transmission route to humans and its potential role in developing and progressing diseases.
KW - Bovine leukemia virus
KW - Epidemiology
KW - Humans
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=85167395731&partnerID=8YFLogxK
U2 - 10.1016/j.virusres.2023.199186
DO - 10.1016/j.virusres.2023.199186
M3 - Artículo en revista científica indexada
C2 - 37532141
AN - SCOPUS:85167395731
SN - 0168-1702
VL - 335
JO - Virus Research
JF - Virus Research
M1 - 199186
ER -
