TY - JOUR
T1 - Coagulopatía asociada con traumatismo Trauma-associated coagulopathy.
AU - Herrera-Almanza, Laura
AU - Martínez-Sánchez, Lina María
A2 - Mercado-Avendaño, Gabriela
A2 - Saavedra-Valencia, Miguel Eduardo
A2 - Carvajal-Alzate, Manuela
A2 - Vergara-Yánez, Daniela
A2 - Cuartas-Agudelo, Yuban Sebastián
N1 - Publisher Copyright:
© 2023 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.
PY - 2023/3
Y1 - 2023/3
N2 - Blood homeostasis can be altered by multiple factors. One of them is trauma, which usually occurs with hemorrhage generating alterations in the coagulation system. When this occurs, it is called trauma-induced coagulopathy. This disease encompasses disseminated intravascular coagulation, for which various factors that increase the risk of suffering from it have been described and various diagnostic scales have been developed. The objective of this review was to gather updated information on disseminated intravascular coagulation in trauma patients, risk factors, pathophysiology, diagnosis, and the use of thromboelastography in this clinical setting to provide key aspects in the adequate care of trauma patients, such as the timely detection of risk of coagulopathy through clinical criteria and the requirement of massive transfusion, which, when properly implemented, reduces the mortality of these patients. A scientific literature search was carried out during January 2021 in the Scielo, PubMed and ScienceDirect databases using the following MeSH descriptors: trauma, disseminated intravascular coagulation, diagnosis, treatment and thromboelastography; 1943 articles were located, of which those that were more up-to-date, exposing the pathophysiology of disseminated intravascular coagulation, the diagnostic criteria, treatment, or the use and advantages of thromboelastography were accepted, rejecting 1886 and selecting 57 articles for writing. Coming up next, a review about the relevant and updated aspects of trauma-induced coagulopathy, in order to bring the reader closer to the use of thromboelastography.
AB - Blood homeostasis can be altered by multiple factors. One of them is trauma, which usually occurs with hemorrhage generating alterations in the coagulation system. When this occurs, it is called trauma-induced coagulopathy. This disease encompasses disseminated intravascular coagulation, for which various factors that increase the risk of suffering from it have been described and various diagnostic scales have been developed. The objective of this review was to gather updated information on disseminated intravascular coagulation in trauma patients, risk factors, pathophysiology, diagnosis, and the use of thromboelastography in this clinical setting to provide key aspects in the adequate care of trauma patients, such as the timely detection of risk of coagulopathy through clinical criteria and the requirement of massive transfusion, which, when properly implemented, reduces the mortality of these patients. A scientific literature search was carried out during January 2021 in the Scielo, PubMed and ScienceDirect databases using the following MeSH descriptors: trauma, disseminated intravascular coagulation, diagnosis, treatment and thromboelastography; 1943 articles were located, of which those that were more up-to-date, exposing the pathophysiology of disseminated intravascular coagulation, the diagnostic criteria, treatment, or the use and advantages of thromboelastography were accepted, rejecting 1886 and selecting 57 articles for writing. Coming up next, a review about the relevant and updated aspects of trauma-induced coagulopathy, in order to bring the reader closer to the use of thromboelastography.
KW - Blood coagulation
KW - Disseminated intravascular coagulation
KW - Thrombelastography
KW - Wounds and Injuries
UR - https://www.scopus.com/pages/publications/85219127449
U2 - 10.24245/mim.v39i2.5490
DO - 10.24245/mim.v39i2.5490
M3 - Artículo de revisión
AN - SCOPUS:85219127449
SN - 0186-4866
VL - 39
SP - 273
EP - 287
JO - Medicina Interna de Mexico
JF - Medicina Interna de Mexico
IS - 2
ER -