Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes

W. Agudelo; Y. Montoya; J. Bustamante

doi:10.1109/GMEPE-PAHCE.2018.8400744

Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes

W. Agudelo
, Y. Montoya
, J. Bustamante

Research output: Chapter in Book/Conference proceeding › Conference and proceedings › peer-review

Abstract

Using disaccharides in green synthesis of metallic nanoparticles (NPs) is an alternative route to traditional processes of nanostructure development, which reduces the degree of incompatibility of these structures with the biological model. The aim of this study was to evaluate the cytotoxic effect of gold and silver nanoparticles synthesized from chemical reduction method with sucrose on in vitro model of cardiomyocytes RL-14. The nanoparticles obtained because of synthesis were characterized by UV-visible spectroscopy, which allowed determining the surface plasmon resonance and experimental particle sizes; likewise, the cell viability assay by MTT was performed to find IC50 of cell growth inhibition of cardiomyocytes. The results showed that variation in cytotoxicity levels are dependent on particle diameter and concentrations of each type of nanostructure.

Original language	English
Title of host publication	2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1-5
Number of pages	5
ISBN (Electronic)	9781538654750
DOIs	https://doi.org/10.1109/GMEPE-PAHCE.2018.8400744
State	Published - 29 Jun 2018
Event	2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018 - Porto, Portugal Duration: 19 Mar 2018 → 24 Mar 2018

Publication series

Name	2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018

Conference

Conference	2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018
Country/Territory	Portugal
City	Porto
Period	19/03/18 → 24/03/18

Bibliographical note

Publisher Copyright:
© 2018 IEEE.

Keywords

Cardiomyocytes
cytotoxicity
metal nanoparticles
sucrose

Types Minciencias

Scientific events with a public engagement component

Access to Document

10.1109/GMEPE-PAHCE.2018.8400744

Cite this

Agudelo, W., Montoya, Y., & Bustamante, J. (2018). Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes. In 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018 (pp. 1-5). (2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/GMEPE-PAHCE.2018.8400744

Agudelo, W. ; Montoya, Y. ; Bustamante, J. / Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes. 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 1-5 (2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018).

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abstract = "Using disaccharides in green synthesis of metallic nanoparticles (NPs) is an alternative route to traditional processes of nanostructure development, which reduces the degree of incompatibility of these structures with the biological model. The aim of this study was to evaluate the cytotoxic effect of gold and silver nanoparticles synthesized from chemical reduction method with sucrose on in vitro model of cardiomyocytes RL-14. The nanoparticles obtained because of synthesis were characterized by UV-visible spectroscopy, which allowed determining the surface plasmon resonance and experimental particle sizes; likewise, the cell viability assay by MTT was performed to find IC50 of cell growth inhibition of cardiomyocytes. The results showed that variation in cytotoxicity levels are dependent on particle diameter and concentrations of each type of nanostructure. ",

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Agudelo, W, Montoya, Y & Bustamante, J 2018, Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes. in 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018. 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018, Institute of Electrical and Electronics Engineers Inc., pp. 1-5, 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018, Porto, Portugal, 19/03/18. https://doi.org/10.1109/GMEPE-PAHCE.2018.8400744

Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes. / Agudelo, W.; Montoya, Y.; Bustamante, J.
2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018. Institute of Electrical and Electronics Engineers Inc., 2018. p. 1-5 (2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018).

Research output: Chapter in Book/Conference proceeding › Conference and proceedings › peer-review

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N2 - Using disaccharides in green synthesis of metallic nanoparticles (NPs) is an alternative route to traditional processes of nanostructure development, which reduces the degree of incompatibility of these structures with the biological model. The aim of this study was to evaluate the cytotoxic effect of gold and silver nanoparticles synthesized from chemical reduction method with sucrose on in vitro model of cardiomyocytes RL-14. The nanoparticles obtained because of synthesis were characterized by UV-visible spectroscopy, which allowed determining the surface plasmon resonance and experimental particle sizes; likewise, the cell viability assay by MTT was performed to find IC50 of cell growth inhibition of cardiomyocytes. The results showed that variation in cytotoxicity levels are dependent on particle diameter and concentrations of each type of nanostructure.

AB - Using disaccharides in green synthesis of metallic nanoparticles (NPs) is an alternative route to traditional processes of nanostructure development, which reduces the degree of incompatibility of these structures with the biological model. The aim of this study was to evaluate the cytotoxic effect of gold and silver nanoparticles synthesized from chemical reduction method with sucrose on in vitro model of cardiomyocytes RL-14. The nanoparticles obtained because of synthesis were characterized by UV-visible spectroscopy, which allowed determining the surface plasmon resonance and experimental particle sizes; likewise, the cell viability assay by MTT was performed to find IC50 of cell growth inhibition of cardiomyocytes. The results showed that variation in cytotoxicity levels are dependent on particle diameter and concentrations of each type of nanostructure.

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Agudelo W, Montoya Y , Bustamante J. Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes. In 2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018. Institute of Electrical and Electronics Engineers Inc. 2018. p. 1-5. (2018 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges, GMEPE/PAHCE 2018). doi: 10.1109/GMEPE-PAHCE.2018.8400744

Cytotoxic effect of gold and silver nanoparticles synthesized by chemical reduction method using sucrose on in vitro model of cardiomyocytes

Abstract

Publication series

Conference

Bibliographical note

Keywords

Types Minciencias

Access to Document

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Cite this