Delirium diagnostic tool-provisional (DDT-Pro) scores in delirium, subsyndromal delirium and no delirium

José G. Franco, Paula T. Trzepacz, Esteban Sepúlveda, María V. Ocampo, Juan D. Velásquez-Tirado, Daniel R. Zaraza, Cristóbal Restrepo, Alejandra M. Giraldo, Paola A. Serna, Adolfo Zuluaga, Carolina López

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    9 Scopus citations


    Objective: To evaluate whether the Delirium Diagnostic Tool-Provisional (DDT-Pro), a 0–9 point scale with three items each representing symptoms from delirium's three core domains, differentiates subsyndromal delirium (SSD) from delirium and no delirium. Methods: We applied cluster analyses of DDT-Pro scores from 200 consecutive inpatients using three reference standards for delirium diagnosis to determine DDT-Pro cutoff values for delirium, SSD and no delirium groups. Clinical validators and DDT-Pro item scores were compared among groups. Results: DDT-Pro SSD range was 6–7 (n = 54), with no delirium having higher scores (n = 98) and delirium lower (n = 48). Dementia prevalence in the SSD group (40.7%) was intermediate between no delirium (20.4%) and delirium (66.7%). SSD and delirium groups were more affected than no delirium regarding medical comorbidities, hospital stay (no delirium <1 week, SSD and delirium >1 week) and mortality (SSD = 7.4%, delirium = 18.8%, no delirium = 1%). Values for motor subtypes, frontal lobe signs, and DRS-R98 in the SSD group were intermediate between no delirium and delirium, as well as for the DDT-Pro items (all p < 0.05). Conclusions: All DDT-Pro items, which represent the three delirium core domains, are important for SSD diagnosis. Patients scoring in the SSD 6–7 range have significant clinical and prognostic features and deserve clinical attention.

    Original languageEnglish
    Pages (from-to)107-114
    Number of pages8
    JournalGeneral Hospital Psychiatry
    StatePublished - 1 Nov 2020

    Bibliographical note

    Funding Information:
    Funding: The Centro de Investigación para El Desarrollo y la Innovación (CIDI) from the Universidad Pontificia Bolivariana , Medellín, Colombia, financed this work. The CIDI did not participate in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the article for publication.

    Publisher Copyright:
    © 2020 Elsevier Inc.


    • Cluster analysis
    • Delirium phenotype
    • Geriatric assessment
    • Psychiatric nosology
    • Psychiatric status rating scales
    • Subsyndromal delirium


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