Determinantes de la falta de conversión de la baciloscopia en pacientes con tuberculosis pulmonar con baciloscopia positiva en Suriname, 2010-2015

Translated title of the contribution: Determinants of sputum smear nonconversion in smear-positive pulmonary tuberculosis patients in Suriname, 2010 - 2015

Eric Commiesie, Deborah Stijnberg, Diana Marín, Freddy Perez, Mauro Sanchez

    Research output: Contribution to journalReview articlepeer-review

    6 Scopus citations

    Abstract

    Objective. To identify factors associated with sputum smear nonconversion in patients with pulmonary tuberculosis (PTB) in Suriname. Methods. A case-control study was conducted using routinely-collected surveillance data of PTB cases reported in January 2010 - December 2015 and recorded in the database of the National Tuberculosis Program of Suriname. Cases were smear-positive PTB patients whose sputum results were negative 2 months after treatment initiation. Controls were the smear-positive PTB patients whose sputum results were negative in the same timeframe. Multivariate logistic regression analysis was used to examine associations between potential risk factors and smear conversion. Results. The two age groups ≥ 35 years (35 - 54 years, AOR: 2.7, 95%CI: 1.2 - 6.1; and 55+ years, AOR: 2.5, 95%CI: 1.1 - 5.9) and high bacillary load at baseline (AOR 2.34, 95%CI: 1.2 - 4.8) were significantly associated with delayed smear conversion. Conclusion. The National TB program of Suriname should develop strategies to address patients at higher risk for delayed smear conversion to prevent further spreading and unfavorable treatment outcomes. To better inform decision-making and future studies, the NTP should expand its data collection to include all risk factors for delayed smear conversion.

    Translated title of the contributionDeterminants of sputum smear nonconversion in smear-positive pulmonary tuberculosis patients in Suriname, 2010 - 2015
    Original languageSpanish
    Article numbere86
    JournalRevista Panamericana de Salud Publica/Pan American Journal of Public Health
    Volume43
    DOIs
    StatePublished - 2019

    Bibliographical note

    Publisher Copyright:
    © 2019 Pan American Health Organization. All rights reserved.

    Fingerprint

    Dive into the research topics of 'Determinants of sputum smear nonconversion in smear-positive pulmonary tuberculosis patients in Suriname, 2010 - 2015'. Together they form a unique fingerprint.

    Cite this