Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds

Monica A. Mejia, Lina M. Hoyos, Jenniffer Zapata, Luz M. Restrepo, Maria E. Moneada

    Research output: Chapter in Book/Report/Conference proceedingConference and proceedingspeer-review

    6 Scopus citations

    Abstract

    The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.

    Original languageEnglish
    Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages4181-4184
    Number of pages4
    ISBN (Electronic)9781457702204
    DOIs
    StatePublished - 13 Oct 2016
    Event38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States
    Duration: 16 Aug 201620 Aug 2016

    Publication series

    NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
    Volume2016-October
    ISSN (Print)1557-170X

    Conference

    Conference38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
    Country/TerritoryUnited States
    CityOrlando
    Period16/08/1620/08/16

    Bibliographical note

    Publisher Copyright:
    © 2016 IEEE.

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