Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds

Monica A. Mejia; Lina M. Hoyos; Jenniffer Zapata; Luz M. Restrepo; Maria E. Moneada

doi:10.1109/EMBC.2016.7591648

Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds

Monica A. Mejia
, Lina M. Hoyos
, Jenniffer Zapata
, Luz M. Restrepo
, Maria E. Moneada

Research output: Chapter in Book/Conference proceeding › Conference and proceedings › peer-review

7 Scopus citations

Abstract

The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.

Original language	English
Title of host publication	2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	4181-4184
Number of pages	4
ISBN (Electronic)	9781457702204
DOIs	https://doi.org/10.1109/EMBC.2016.7591648
State	Published - 13 Oct 2016
Event	38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 - Orlando, United States Duration: 16 Aug 2016 → 20 Aug 2016

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume	2016-October
ISSN (Print)	1557-170X

Conference

Conference	38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016
Country/Territory	United States
City	Orlando
Period	16/08/16 → 20/08/16

Bibliographical note

Publisher Copyright:
© 2016 IEEE.

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10.1109/EMBC.2016.7591648

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Mejia, M. A., Hoyos, L. M., Zapata, J., Restrepo, L. M., & Moneada, M. E. (2016). Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016 (pp. 4181-4184). Article 7591648 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2016-October). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2016.7591648

Mejia, Monica A. ; Hoyos, Lina M. ; Zapata, Jenniffer et al. / Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds. 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., 2016. pp. 4181-4184 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds",

abstract = "The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.",

author = "Mejia, \{Monica A.\} and Hoyos, \{Lina M.\} and Jenniffer Zapata and Restrepo, \{Luz M.\} and Moneada, \{Maria E.\}",

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Mejia, MA, Hoyos, LM, Zapata, J, Restrepo, LM & Moneada, ME 2016, Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds. in 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016., 7591648, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2016-October, Institute of Electrical and Electronics Engineers Inc., pp. 4181-4184, 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016, Orlando, United States, 16/08/16. https://doi.org/10.1109/EMBC.2016.7591648

Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds. / Mejia, Monica A.; Hoyos, Lina M.; Zapata, Jenniffer et al.
2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., 2016. p. 4181-4184 7591648 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2016-October).

Research output: Chapter in Book/Conference proceeding › Conference and proceedings › peer-review

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AU - Mejia, Monica A.

AU - Hoyos, Lina M.

AU - Zapata, Jenniffer

AU - Restrepo, Luz M.

AU - Moneada, Maria E.

PY - 2016/10/13

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N2 - The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.

AB - The nanofibres created by electrospinning technique are currently used for a variety of applications in tissue engineering; and Gelatin and Polyurethane Shape-Memory (SMPU) have important results in biomedicine. Similarly, carbon nanotubes combined with other biomaterials change important properties, opening new opportunities for biomedical applications. In this work, we constructed scaffold using electrospinning technique based in bovine-hide gelatin, SMPU and both materials hybrid with carbon nanotube. Morphology and cytotoxicity were evaluated and mechanical properties for two materials were obtained in scaffold building. Morphological, mechanical and citotoxic properties of the electrospun fibers were found to be dependent of alteration in materials concentration, electrospinning conditions and MWCNT concentration. According to morphological, cytotoxic and mechanical analysis, SMPU more MWCNT were the best material, with nanofibers of 451 nm, tensile strength of 1.912 MPa, and a high ratio surface volume.

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Y2 - 16 August 2016 through 20 August 2016

ER -

Mejia MA, Hoyos LM, Zapata J, Restrepo LM, Moneada ME. Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds. In 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc. 2016. p. 4181-4184. 7591648. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2016.7591648

Electrospinning of gelatin and SMPU with carbon nanotubes for tissue engineering scaffolds

Abstract

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