Fractal analysis of neuroimaging: comparison between control patients and patients with the presence of Alzheimer's disease

J. Villamizar, L. Uribe, A. Cerquera, E. Prada, D. Prada, M. Alvarez

    Research output: Contribution to journalConference articlepeer-review


    Alzheimer's disease is a neurodegenerative cognitive, affective, and behavioral disorder aligned to the aging process and other coronary diseases. To contribute to the early diagnosis of the disease, a neuroimaging treatment is implemented through a preprocessing to subsequently calculate the fractal dimension associated with these images in order to propose an alternative to the one proposed in medical physics through positron emission tomography. In this work, a comparative analysis is made of a previous work using the Box Counting methodology versus the calculation of the fractal dimension by means of software developed by the researchers based on the same method. The differences between the fractal dimensions of the neuroimages of control patients and patients with the presence of the disease are maintained showing a lower value of fractal dimension in patients with the disease due to the physical deterioration of the brain.

    Original languageEnglish
    Article number012011
    JournalJournal of Physics: Conference Series
    Issue number1
    StatePublished - 5 Jan 2022
    Event8th International Conference Days of Applied Mathematics, ICDAM 2021 - San Jose de Cucuta, Colombia
    Duration: 20 Oct 202122 Oct 2021

    Bibliographical note

    Funding Information:
    The authors offer they're thanks to Universidad Pontificia Bolivariana, Colombia, and the Ministerio de Ciencia, Tecnolog?a e Innovaci?n, Colombia, within the framework of the Project Creation and implementation of a multicomponent diagnostic evaluation protocol in patients with major neurocognitive disorder (TNC) Alzheimer's type: A multidisciplinary study through the use of fractal geometry in brain images.

    Publisher Copyright:
    © 2022 Institute of Physics Publishing. All rights reserved.


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