Impact of My Dose Coach App Frequency of Use on Clinical Outcomes in Type 2 Diabetes

Ambika Gopalakrishnan Unnikrishnan, Vijay Viswanathan, Fang Liz Zhou, Lichen Hao, Prithvi Kamath, Monica Bertolini, Jose Fernando Botero, Leonardo Mancillas-Adame

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Introduction: My Dose Coach (MDC) is a US Food and Drug Administration-approved digital smartphone application designed to help users with type 2 diabetes (T2D) titrate their basal insulin (BI) according to a clinician-prescribed individualized titration plan. The aim of this analysis was to assess the impact of the frequency of MDC use on clinical outcomes. Methods: This retrospective observational analysis included people with T2D who were registered for MDC (August 1st, 2018–April 30th, 2020) and received BI. Users with an activated care plan and ≥2 fasting blood glucose (FBG) observations spanning ≥2 weeks were defined as active. Outcomes included percentage achieving their individual FBG target, time to FBG target, change in FBG, change in insulin dose and hypoglycemia. Users were stratified into high (>3 days per week), moderate (>1– ≤3 days per week), and low (≤1 day per week) MDC usage groups. Results: The analysis included 2517 active MDC users. Approximately 49% of users had high MDC usage. Overall, 44% of users across all usage frequencies achieved their individual FBG target. High MDC use was associated with significantly better FBG target achievement and less time to FBG target versus moderate- and low-usage groups (p≤0.01 for all). Insulin dose change was significantly greater in the high- versus moderate-usage group (p=0.01). There was no significant difference in hypoglycemia incidence among MDC usage groups (12%–16% of users in any usage group). Conclusions: More frequent MDC usage was associated with better FBG outcomes without increased hypoglycemia risk.

    Original languageEnglish
    JournalDiabetes Therapy
    DOIs
    StateAccepted/In press - 2022

    Bibliographical note

    Funding Information:
    This study and Rapid Service Fee was funded by Sanofi.

    Publisher Copyright:
    © 2022, The Author(s).

    Keywords

    • Glycemic control
    • Mobile application
    • Self-management
    • Type 2 diabetes mellitus

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