TY - JOUR
T1 - Malakoplakia after kidney transplantation
T2 - Case report and literature review
AU - Nieto-Ríos, John Fredy
AU - Ramírez, Isabel
AU - Zuluaga-Quintero, Mónica
AU - Serna-Higuita, Lina María
AU - Gaviria-Gil, Federico
AU - Velez-Hoyos, Alejandro
N1 - Publisher Copyright:
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
PY - 2017/10
Y1 - 2017/10
N2 - Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r-UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r-UTI from Escherichia coli in a patient with renal transplantation, refractory to long-term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT.
AB - Malakoplakia is a granulomatous disease associated with an infectious etiology, usually involving the urinary tract. It reveals itself as a recurrent urinary tract infection (r-UTI), and in some cases, it is associated with impairment of renal function. Immunosuppression is one of its main associated factors, and it has been increasingly described in patients with solid organ transplantation (SOT), mainly kidney transplantation. Macroscopically, it can form masses and sometimes it may be confused with neoplasia, which is why histological findings are fundamental for the diagnosis. Here, we present a case of bladder malakoplakia, manifested by r-UTI from Escherichia coli in a patient with renal transplantation, refractory to long-term antibiotic treatment and reduction in immunosuppression, which resolved after surgical management. We also summarize the clinical characteristics of malakoplakia and compare them with previous reports in the literature on SOT.
KW - Escherichia coli
KW - immunosuppression
KW - kidney transplantation
KW - malakoplakia
KW - urinary tract infection
UR - http://www.scopus.com/inward/record.url?scp=85023183048&partnerID=8YFLogxK
U2 - 10.1111/tid.12731
DO - 10.1111/tid.12731
M3 - Artículo en revista científica indexada
C2 - 28561517
AN - SCOPUS:85023183048
SN - 1398-2273
VL - 19
JO - Transplant Infectious Disease
JF - Transplant Infectious Disease
IS - 5
M1 - e12731
ER -
