MicroARN: la biología molecular como herramienta de predicción en preeclampsia

E. Sánchez Díaz; L. M. Martínez-Sánchez; M. D. Roldan Tabares; L. I. Jaramillo Jaramillo

doi:10.1016/j.gine.2021.100740

MicroARN: la biología molecular como herramienta de predicción en preeclampsia

Translated title of the contribution: MicroRNAs: molecular biology as a tool for preeclampsia prediction

E. Sánchez Díaz, L. M. Martínez-Sánchez, M. D. Roldan Tabares, L. I. Jaramillo Jaramillo

Research output: Contribution to journal › Review article › peer-review

Abstract

Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.

Translated title of the contribution	MicroRNAs: molecular biology as a tool for preeclampsia prediction
Original language	Spanish
Article number	100740
Journal	Clinica e Investigacion en Ginecologia y Obstetricia
Volume	49
Issue number	2
DOIs	https://doi.org/10.1016/j.gine.2021.100740
State	Published - 1 Apr 2022

Bibliographical note

Publisher Copyright:
© 2021 Elsevier España, S.L.U.

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title = "MicroARN: la biolog{\'i}a molecular como herramienta de predicci{\'o}n en preeclampsia",

abstract = "Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.",

keywords = "Hypertension, Molecular biology, Preeclampsia",

author = "{S{\'a}nchez D{\'i}az}, E. and Mart{\'i}nez-S{\'a}nchez, {L. M.} and {Roldan Tabares}, {M. D.} and {Jaramillo Jaramillo}, {L. I.}",

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doi = "10.1016/j.gine.2021.100740",

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T2 - la biología molecular como herramienta de predicción en preeclampsia

AU - Sánchez Díaz, E.

AU - Martínez-Sánchez, L. M.

AU - Roldan Tabares, M. D.

AU - Jaramillo Jaramillo, L. I.

PY - 2022/4/1

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AB - Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.

KW - Hypertension

KW - Molecular biology

KW - Preeclampsia

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U2 - 10.1016/j.gine.2021.100740

DO - 10.1016/j.gine.2021.100740

M3 - Artículo de revisión

AN - SCOPUS:85123007359

VL - 49

JO - Clinica e Investigacion en Ginecologia y Obstetricia

JF - Clinica e Investigacion en Ginecologia y Obstetricia

SN - 0210-573X

IS - 2

M1 - 100740

ER -

MicroARN: la biología molecular como herramienta de predicción en preeclampsia

Abstract

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