Mycobacterium abscessus complex: A Review of Recent Developments in an Emerging Pathogen

Laura Victoria, Amolika Gupta, Jose Luis Gómez, Jaime Robledo

    Research output: Contribution to journalReview articlepeer-review

    11 Scopus citations

    Abstract

    Mycobacterium abscessus complex (MABC) is one of the most clinically relevant species among nontuberculous mycobacteria. MABC’s prevalence has increased over the last two decades. Although these changes can be explained by improvements in microbiological and molecular techniques for identifying species and subspecies, a higher prevalence of chronic lung diseases may contribute to higher rates of MABC. High rates of antimicrobial resistance are seen in MABC, and patients experience multiple relapses with low cure rates. This review aims to integrate existing knowledge about MABC epidemiology, microbiological identification and familiarize readers with molecular mechanisms of resistance and therapeutic options for pulmonary infections with MABC.

    Original languageEnglish
    Article number659997
    JournalFrontiers in Cellular and Infection Microbiology
    Volume11
    DOIs
    StatePublished - 26 Apr 2021

    Bibliographical note

    Publisher Copyright:
    © Copyright © 2021 Victoria, Gupta, Gómez and Robledo.

    Keywords

    • epidemiology
    • infection
    • lung
    • Mycobacterium abscessus
    • resistance
    • treatment

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