Renal amyloidosis in ankylosing spondylitis: A case report

Juan David Romero-Marín; Yeison Cantor; Esteban Prieto-Bravo; Reinaldo Sierra-Rosales; Adriana Flórez-Vargas; Miguel Antonio Mesa-Navas; Carlos Jaime Velásquez-Franco

doi:10.1016/j.rcreu.2019.04.004

Renal amyloidosis in ankylosing spondylitis: A case report

Juan David Romero-Marín
, Yeison Cantor
, Esteban Prieto-Bravo
, Reinaldo Sierra-Rosales
, Adriana Flórez-Vargas
, Miguel Antonio Mesa-Navas
, Carlos Jaime Velásquez-Franco

Research output: Contribution to journal › Article in an indexed scientific journal › peer-review

1 Scopus citations

Abstract

Renal manifestations of spondyloarthritis are rare. The case is presented of a patient with ankylosing spondylitis of nine years of evolution. He had intense inflammation, as well as articular sequelae, with a significant deterioration in his quality of life. At the initial evaluation, the patient had a serum creatinine of 1.44 mg/dL and a 24-h urine protein in the sub-nephrotic range (1.44 g). Renal biopsy showed the presence of Congophilic material, confirming the diagnosis of AA amyloidosis. Treatment with a TNF blocking agent was initiated with clinical improvement, especially regarding articular disease.

Original language	Spanish (Colombia)
Pages (from-to)	46-49
Number of pages	4
Journal	Revista Colombiana de Reumatologia
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/j.rcreu.2019.04.004
State	Published - Jan 2020
Externally published	Yes

Types Minciencias

Artículos de investigación con calidad Q4

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.rcreu.2019.04.004

Cite this

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title = "Renal amyloidosis in ankylosing spondylitis: A case report",

abstract = "Renal manifestations of spondyloarthritis are rare. The case is presented of a patient with ankylosing spondylitis of nine years of evolution. He had intense inflammation, as well as articular sequelae, with a significant deterioration in his quality of life. At the initial evaluation, the patient had a serum creatinine of 1.44 mg/dL and a 24-h urine protein in the sub-nephrotic range (1.44 g). Renal biopsy showed the presence of Congophilic material, confirming the diagnosis of AA amyloidosis. Treatment with a TNF blocking agent was initiated with clinical improvement, especially regarding articular disease.",

keywords = "Amyloidosis, Ankylosing Spondylitis, Kidney",

author = "Romero-Mar{\'i}n, \{Juan David\} and Yeison Cantor and Esteban Prieto-Bravo and Reinaldo Sierra-Rosales and Adriana Fl{\'o}rez-Vargas and Mesa-Navas, \{Miguel Antonio\} and Vel{\'a}squez-Franco, \{Carlos Jaime\}",

year = "2020",

month = jan,

doi = "10.1016/j.rcreu.2019.04.004",

language = "Espa{\~n}ol (Colombia)",

volume = "27",

pages = "46--49",

journal = "Revista Colombiana de Reumatologia",

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publisher = "Asociacion Colombiana de Reumatologia",

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}

TY - JOUR

T1 - Renal amyloidosis in ankylosing spondylitis: A case report

AU - Romero-Marín, Juan David

AU - Cantor, Yeison

AU - Prieto-Bravo, Esteban

AU - Sierra-Rosales, Reinaldo

AU - Flórez-Vargas, Adriana

AU - Mesa-Navas, Miguel Antonio

AU - Velásquez-Franco, Carlos Jaime

PY - 2020/1

Y1 - 2020/1

N2 - Renal manifestations of spondyloarthritis are rare. The case is presented of a patient with ankylosing spondylitis of nine years of evolution. He had intense inflammation, as well as articular sequelae, with a significant deterioration in his quality of life. At the initial evaluation, the patient had a serum creatinine of 1.44 mg/dL and a 24-h urine protein in the sub-nephrotic range (1.44 g). Renal biopsy showed the presence of Congophilic material, confirming the diagnosis of AA amyloidosis. Treatment with a TNF blocking agent was initiated with clinical improvement, especially regarding articular disease.

AB - Renal manifestations of spondyloarthritis are rare. The case is presented of a patient with ankylosing spondylitis of nine years of evolution. He had intense inflammation, as well as articular sequelae, with a significant deterioration in his quality of life. At the initial evaluation, the patient had a serum creatinine of 1.44 mg/dL and a 24-h urine protein in the sub-nephrotic range (1.44 g). Renal biopsy showed the presence of Congophilic material, confirming the diagnosis of AA amyloidosis. Treatment with a TNF blocking agent was initiated with clinical improvement, especially regarding articular disease.

KW - Amyloidosis

KW - Ankylosing Spondylitis

KW - Kidney

UR - https://www.mendeley.com/catalogue/d37108d3-3b78-32a1-8df5-e43ae3785ebe/

U2 - 10.1016/j.rcreu.2019.04.004

DO - 10.1016/j.rcreu.2019.04.004

M3 - Artículo en revista científica indexada

SN - 0121-8123

VL - 27

SP - 46

EP - 49

JO - Revista Colombiana de Reumatologia

JF - Revista Colombiana de Reumatologia

IS - 1

ER -