Resistencia a ertapenem en 2 instituciones hospitalarias de alto nivel de complejidad: microbiología, epidemiología y factores de riesgo

Translated title of the contribution: Ertapenem resistance in 2 tertiary-care hospitals: Microbiology, epidemiology, and risk factors

Natalia Maldonado, Bibiana Castro, Indira Berrio, Miguel Manjarrés, Carlos Robledo, Jaime Robledo

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations

    Abstract

    Introduction Carbapenems resistance is a growing phenomenon and a threat to public health because of the reduced therapeutic options for resistant infections. Methods A retrospective case-control study was conducted in 2 tertiary-care hospitals in Medellín, Colombia. Fifty patients infected with ertapenem-resistant enterobacteriaceae were compared with a control group consisting of 100 patients with infections caused by ertapenem susceptible enterobacteriaceae. A multivariate logistic regression model was used to identify factors that best explain ertapenem-resistant enterobacteriaceae infections. Results The factors associated with ertapenem-resistant enterobacteriaceae infections were prior exposure to carbapenems (adjusted OR 3.43; 95% IC 1.08-10.87) and prior exposure to cefepime (adjusted OR 6.46; 95% IC 1.08-38.38). Conclusion Prior exposure to antibiotics is the factor that best explains the ertapenem-resistant enterobacteriaceae infection in this population, highlighting the importance of antimicrobial stewardship programs in hospitals.

    Translated title of the contributionErtapenem resistance in 2 tertiary-care hospitals: Microbiology, epidemiology, and risk factors
    Original languageSpanish
    Pages (from-to)511-515
    Number of pages5
    JournalEnfermedades Infecciosas y Microbiologia Clinica
    Volume35
    Issue number8
    DOIs
    StatePublished - Oct 2017

    Bibliographical note

    Publisher Copyright:
    © 2015 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica

    Fingerprint

    Dive into the research topics of 'Ertapenem resistance in 2 tertiary-care hospitals: Microbiology, epidemiology, and risk factors'. Together they form a unique fingerprint.

    Cite this