Seroprevalencia de los virus linfotrópicos de células T humanas de tipos I y II en donantes del Banco de Sangre del Hospital Pablo Tobón Uribe, entre 2014 y 2015

Translated title of the contribution: HTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015

Manuela Muñoz, Santiago Carvalho, Jorge Hernando Donado, Gloria Eugenia Barco, Sergio Jaramillo

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations

    Abstract

    Introduction: The human-T cell lymphotropic virus is a retrovirus with various types known so far. HTLV-I and HTLV-II are of clinically importance as they cause different diseases such as adult T-cell leukemia/lymphoma, tropical spastic paraparesis, and human T-lymphotropic virus type I-associated myelopathy (HAM). Objective: To estimate the prevalence of presumptive and confirmatory reactivity to HTLV-I/II in blood donors of Hospital Pablo Tobón Uribe Blood Bank between 2014 and 2015. Materials and methods: The information was obtained from the Hospital Pablo Tobón Uribe Blood Bank database. We analyzed age, sex, place of origin, and place of residence of donors, and the reactivity using the screening test (ELISA) as well as the confirmatory test (immunoblot). Results: The donor population studied included 6,275 men and 8,148 women, for a total of 14,423 donors recruited between March 1, 2014, and June 30, 2015. Of all tested donors, 25 were positive for HTLV-I/II by the screening test (ELISA). After performing the confirmatory test (immunoblot), only nine patients were positive for HTLV-I/II (36%), of whom eight were reactive to HTLV-I (32%) and one to HTLV-II (4%), for a global seroprevalence of 0.06% (CI 95%: 0.10-0.25). Conclusions: Our findings were consistent with those found in similar studies in non-endemic areas of the country and with those from studies at international level reported in the literature.

    Translated title of the contributionHTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015
    Original languageSpanish
    Pages (from-to)37-41
    Number of pages5
    JournalBiomedica
    Volume38
    Issue number1
    DOIs
    StatePublished - 2018

    Bibliographical note

    Funding Information:
    micropartículas (Chemiluminescence Microparticle ImmunoAssay, CMIA) con el sistema Architect (Abbott, Alemania) para la detección cualitativa de anticuerpos para el HTLV de tipos I y II en suero y plasma en todos los donantes del Banco de Sangre del Hospital.

    Publisher Copyright:
    © Biomédica 2018.

    Fingerprint

    Dive into the research topics of 'HTLV-I/II seroprevalence in blood donors of Hospital Pablo Tobón Uribe Blood Bank during the period 2014-2015'. Together they form a unique fingerprint.

    Cite this