Virome analysis of three Ixodidae ticks species from Colombia: A potential strategy for discovering and surveying tick-borne viruses

Mateo Orozco Orozco, Giovan F. Gómez, Juan F. Alzate, Juan P. Isaza, Lina A. Gutiérrez

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Ticks are a group of obligate blood-sucking ectoparasites that play a critical role in transmitting several important zoonotic pathogens that can infect animals and humans. Viruses are part of the tick microbiome and are involved in the transmission of important diseases. Furthermore, the little information on these as etiological agents of zoonoses suggests the need to study these microorganisms. For this reason, in this study, we sought to characterize the virome in Rhipicephalus microplus, Dermacentor nitens, and Rhipicephalus sanguineus s.l., which were collected from different domestic animals in Antioquia, Colombia. RNA sequencing was used for virome characterization in these three tick species, using RNA-dependent polymerase as a marker gene. Forty-eight sequences corresponding to 14 different viruses were identified, some of which were previously identified in the tick's virome. Overall, these data indicate that ticks from domestic animals in cattle farms harbor a wide viral diversity at the local scale. Thus, the metatranscriptomic approach provides important baseline information for monitoring the tick virome and to develop future studies on their biology, host-virus interactions, host range, worldwide distribution, and finally, their potential role as emerging vector-borne agents.

    Original languageEnglish
    Article number105103
    JournalInfection, Genetics and Evolution
    Volume96
    DOIs
    StatePublished - Dec 2021

    Bibliographical note

    Funding Information:
    This work was supported by Minciencias (Ministerio de Ciencia Tecnolog?a e Innovaci?n), Colombia, Project code C145I000000008166?1, convocatoria 784?2017, and Direcci?n de Investigaci?n y Transferencia - CIDI, Universidad Pontificia Bolivariana (UPB), CIDI codes 823B-06/17?55 and 042C-02/18?65. MOO was involved such a undergraduate student in training in the grant supported by Minciencias contract 692?2017 and CIDI UPB number 020C-01/18?65.

    Funding Information:
    This work was supported by Minciencias (Ministerio de Ciencia Tecnología e Innovación) , Colombia, Project code C145I000000008166–1 , convocatoria 784–2017, and Dirección de Investigación y Transferencia - CIDI, Universidad Pontificia Bolivariana (UPB), CIDI codes 823B-06/17–55 and 042C-02/18–65 . MOO was involved such a undergraduate student in training in the grant supported by Minciencias contract 692–2017 and CIDI UPB number 020C-01/18–65 .

    Publisher Copyright:
    © 2021 The Authors

    Keywords

    • Dermacentor nitens
    • Rhipicephalus microplus
    • Rhipicephalus sanguineus s.l.
    • Tick-borne diseases
    • Zoonoses

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