α'H -Dicalcium silicate bone cement doped with tricalcium phosphate: Characterization, bioactivity and biocompatibility

Piedad N. De Aza, Fausto Zuleta, Pablo Velasquez, Nestor Vicente-Salar, Juan A. Reig

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

14 Citas (Scopus)

Resumen

The influence of phosphorus doping on the properties of α' H -dicalcium silicate (C2S) bone cement was analyzed, in addition to bioactivity and biocompatibility. All the cements were composed of a solid solution of TCP in C2S (α'H} α H ′ -C2Sss) as the only phase present. The compressive strength ranged from 3.8-16.3 MPa. Final setting times ranged from 10 to 50 min and were lower for cements with lower L/P content. Calcium silicate hydrate was the principal phase formed during the hydration process of the cements. The cement exhibited a moderate degradation and could induce carbonated hydroxyapatite formation on its surface and into the pores. The cell attachment test showed that the α'H -Ca2SiO4 solid solution supported human adipose stem cells adhesion and spreading, and the cells established close contacts with the cement after 24 h of culture. The novel α'H -C2Sss cements might be suitable for potential applications in the biomedical field, preferentially as materials for bone/dental repair.

Idioma originalInglés
Páginas (desde-hasta)445-452
Número de páginas8
PublicaciónJournal of Materials Science: Materials in Medicine
Volumen25
N.º2
DOI
EstadoPublicada - feb. 2014
Publicado de forma externa

Huella

Profundice en los temas de investigación de 'α'H -Dicalcium silicate bone cement doped with tricalcium phosphate: Characterization, bioactivity and biocompatibility'. En conjunto forman una huella única.

Citar esto