Anticoagulación oral: un reto para el apego terapéutico

Lina María Martínez-Sánchez, Andrea Urrego-Vásquez, Juan Ricardo Gaviria-García, Juan Pablo Ospina-Sánchez, Laura Isabel Jaramillo-Jaramillo, Felipe Hernández-Restrepo

Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva


Oral anticoagulants have been a great ally for physicians in thromboembolic events because they represent a great challenge in their management, causing a high number of deaths in developed countries. Several drugs have been created, such as vitamin K antagonists, that require strict monitoring, over time, molecules known as the direct oral anticoagulants have been developed, these have allowed their administration to be safer and not have to carry out such strict controls. This paper reviews bibliography on the characteristics and therapeutic adherence of direct oral anticoagulants and how they impact thrombotic events. Literature review was carried out, searching for original articles and systematic reviews in PubMed and ScienceDirect. We selected 80 articles, included 52 that fulfilled the stated objective, from these the description of the present text was developed in which aspects related to the epidemiology, pharmacology and adherence of direct oral anticoagulants are developed. Direct oral anticoagulants are drugs that are increasingly prescribed by specialists because they provide greater patient safety but require adequate adherence by these patients to achieve the expected therapeutic effect.

Título traducido de la contribuciónOral anticoagulants: A challenge in therapeutic adherence.
Idioma originalEspañol
Páginas (desde-hasta)355-365
Número de páginas11
PublicaciónMedicina Interna de Mexico
EstadoPublicada - mar. 2022
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2022 Comunicaciones Cientificas Mexicanas S.A. de C.V.. All rights reserved.

Palabras clave

  • Anticoagulants
  • Medication adherence
  • Therapeutic adherence
  • Warfarin

Tipos de Productos Minciencias

  • Artículos de investigación con calidad Q4


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