Antiphospholipid antibodies, steroid dose, arterial hypertension, relapses, and late-onset predict organ damage in a population of Colombian patients with systemic lupus erythematosus

Luis F. Pinto-Peñaranda, C. Muñoz-Grajales, A. F. Echeverri Garcia, C. J. Velásquez-Franco, M. A. Mesa-Navas, M. Zuluaga Quintero, S. Herrera-Uribe, J. D. Márquez-Hernández

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7 Citas (Scopus)

Resumen

Organ damage predicts mortality, increased accrual of detriment, and poor quality of life in systemic lupus erythematosus patients. The objective of this study is to determine the damage-free survival and its predictive factors in a population of Colombian subjects. The method used in this study is the retrospective follow-up of a cohort; damage was measured with SLICC/ACR index. Predictors of impairment were assessed by logistic regression and survival analysis. One hundred sixty-one individuals were included; 28.9% suffered damage, primarily neuropsychiatric, renal, and vascular. Arterial hypertension, antiphospholipid antibodies, prednisone dose, and number of relapses were all predictors of detriment. Onset after age 50 and daily prednisone dose higher than 7.5 mg determined earlier occurrence of damage.
Idioma originalInglés
Páginas (desde-hasta)949-954
Número de páginas6
PublicaciónClinical Rheumatology
Volumen37
N.º4
DOI
EstadoPublicada - 1 abr. 2018

Nota bibliográfica

Publisher Copyright:
© 2017, International League of Associations for Rheumatology (ILAR).

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  • Artículos de investigación con calidad A1 / Q1

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