Behcet's disease: Experience in a Colombian cohort

Título traducido de la contribución: Enfermedad de Behcet: experiencia en una cohorte de pacientes colombianos

Ana Milena Toro Giraldo, Luis Fernando Pinto Peñaranda, Carlos Jaime Velásquez Franco, José Luis Torres Grajales, Dora Liliana Candia Zúñiga, Javier Darío Márquez Hernández

Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva

8 Citas (Scopus)

Resumen

Background Behcet's disease (BD) is a multisystemic vasculitis of unknown cause. It is characterized by exacerbations and remissions of unpredictable duration. The clinical findings include oral and genital aphtaes, arthritis, cutaneous lesions, ocular, gastrointestinal and neurological manifestations. In our environment, the natural course, activity and severity of BD is not fully known. Objectives the purpose of this research is to describe the clinical spectrum, activity and severity of BD in a group of Colombian patients. Methods a longitudinal, observational, descriptive and prospective study was realized in a group of patients with BD, who were evaluated and followed for the rheumatology department at the Hospital Pablo Tobón Uribe, Medellín, Colombia. Results 20 patients (15 women and 5 men) were found, with an average of 42.1 ± 11.2 years old at diagnosis. The most common clinical manifestations were the oral (95%) and genital (75%) ulcers, followed by cutaneous (60%), ocular (55%), articular (45%), gastrointestinal (40%), vascular (15%) and neurological (15%) involvement. The recurrent oral ulcers were the most common onset manifestation. The mean duration between the onset symptom and the fulfillment of diagnostic criteria was 4.45 ± 4.19 years. 50% patients were classified as having moderate disease and 35% as having severe disease. Conclusions BD is an underdiagnosed disease in our environment. The mucocutaneous ulcers represent the main clinical finding and can precede other manifestations for a long time, causing a delay in diagnosis and allowing an aggressive behavior.

Título traducido de la contribuciónEnfermedad de Behcet: experiencia en una cohorte de pacientes colombianos
Idioma originalInglés
Páginas (desde-hasta)33-45
Número de páginas13
PublicaciónRevista Colombiana de Reumatologia
Volumen16
N.º1
DOI
EstadoPublicada - 1 mar. 2009
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2009 Asociación Colombiana de Reumatología

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