Características clínicas y microbiológicas de la infección intra-abdominal complicada en Colombia: Un estudio multicéntrico

Marta Vallejo, Diana P. Cuesta, Luz E. Flórez, Adriana Correa, Carmen E. Llanos, Berenice Isaza, Stella Vanegas, Johanna Osorio, Lucía Casanova, María V. Villegas

    Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

    6 Citas (Scopus)

    Resumen

    Introduction: Complicated community-acquired intra-abdominal infections (CA-cIAI) are a common cause of acute abdomen. Objective: To identify the clinical and microbiology profile of CA-cIAI in four Colombian hospitals. Methods: This is a prospective, descriptive study, between 08-2012 and 09-2014, including patients with CA-cIAI ≥ 15 years. Data collected included: socio-demographic, clinical, diagnosis, and isolates of the first culture obtained aseptically during surgery with antimicrobial susceptibility. Results: 192 patients were included, 62% men, median age 47.3 years. Co-morbidities were present in 38.4%, 13% had been hospitalized in the previous year 13%, and 9.4% had received antibiotics in the last 6 months; 44.3% were admitted for appendicitis, 17.7% for peritonitis and 16.7% for bowel perforation. CA-cIAI were assessed as moderate in 64.1% of the cases and were treated with ampicillin/sulbactam (SAM) and ertapenem. In 70.8% of cases a bacteria was isolated: 65.1% were gramnegative rods (80.0% Escherichia coli, 44.8% of them susceptible to pipercillin/tazobactam, 65.7% to SAM; 11.2 % were K. pneumoniae, 85% was susceptible for SAM; 16.7% were grampositive cocci (28.1% Streptococci viridans group). The median hospital stay was 7 days and 15.1% died. Conclusions: E. coli, K. pneumoniae and S. viridans were the main organisms to consider in an empiric therapy for CA-cIAI and it is important to know the local epidemiology in order to choose the right antibiotic.

    Título traducido de la contribuciónClinical and microbiological characteristics of complicated intra-abdominal infection in Colombia: A multicenter study
    Idioma originalEspañol
    Páginas (desde-hasta)261-267
    Número de páginas7
    PublicaciónRevista Chilena de Infectologia
    Volumen33
    N.º3
    DOI
    EstadoPublicada - jun. 2016

    Nota bibliográfica

    Publisher Copyright:
    © 2016, Sociedad Chilena de Infectologia. All rights reserved.

    Palabras clave

    • Abdominal infection
    • Microbial; community-acquired infections
    • Peritonitis/microbiology; drug resistance

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