Clinical features and prognostic factors of adults with COVID-19 admitted to intensive care units in Colombia: A multicentre retrospective study during the first wave of the pandemic

Título traducido de la contribución: Características clínicas y factores pronósticos de adultos con COVID-19 ingresados en unidades de cuidados intensivos en Colombia: un estudio retrospectivo multicéntrico durante la primera ola pandémica

the RAMCOVID study group

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5 Citas (Scopus)

Resumen

Background: A significant number of COVID-19 patients require intensive care unit (ICU) admission. However, ICU mortality in COVID-19 patients varies considerably between studies. Objectives: To determine the clinical features and outcomes of adults with COVID-19 admitted to ICU in Colombia during the first wave of the pandemic. Material and methods: A multicentre retrospective study was carried out in 8 ICUs. Adult patients admitted to the ICU with confirmed SARS-CoV-2 infection from March to July of 2020 were included. Results: During the study period, 229 adults with COVID-19 were admitted to ICU. Most patients (54.5%) were older than 65 years. Comorbid conditions were documented in 146 (64%) patients, mainly arterial hypertension and diabetes mellitus. The median value of the SOFA score on ICU admission was 5 (interquartile range, 2–12). Regarding complications, 118 (51.5%) underwent mechanical ventilation, 51 (22.4%) required renal replacement therapy, and 85 (35%), vasopressor use. Mortality was 38.4% (88 out of 219 patients). Mortality increased with age (20% in those younger than 40 years and 54.1% in those older than 65 years; p < .001). In the multivariate analysis, independent factors associated with mortality were age ≥ 65 years (OR, 11.9; 95% CI, 3.20–44.23), SOFA score (OR, 1.21; 95% CI, 1.05–1.39), vasopressor use (OR, 12.8; 95% CI, 3.45–48.17), and renal replacement therapy (OR, 9.0; 95% CI 2.37–34.42). Conclusions: Critically ill patients with COVID-19 had high mortality mainly related to advanced age, the severity of the disease on admission to the ICU, the use of vasopressors and renal replacement therapy.

Título traducido de la contribuciónCaracterísticas clínicas y factores pronósticos de adultos con COVID-19 ingresados en unidades de cuidados intensivos en Colombia: un estudio retrospectivo multicéntrico durante la primera ola pandémica
Idioma originalInglés
Páginas (desde-hasta)95-99
Número de páginas5
PublicaciónActa Colombiana de Cuidado Intensivo
Volumen22
N.º2
DOI
EstadoPublicada - 1 abr. 2022
Publicado de forma externa

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Publisher Copyright:
© 2021 Asociación Colombiana de Medicina Crítica y Cuidado lntensivo

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