Coagulación intravascular diseminada y sepsis: Tratamiento y criterios diagnósticos

Lina María Martínez Sánchez, Gabriela Mercado Avendaño

    Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva


    Introduction: Sepsis is a pathological process characterized by inordinate inflammation which may cause severe coagulopathies, such as disseminated intravascular coagulation. This coagulopathy is mainly characterized by exposure of the tissue factor, activating the coagulation cascade and generating a prothrombotic state which may worsen organ failure. Objective: Analyze diagnostic criteria and therapeutic implications to present an update on the management of patients with disseminated intravascular coagulation and sepsis. Methods: A search was conducted for papers published in the databases PubMed, Science Direct and SciELO, using the search terms coagulopathy, sepsis, disseminated intravascular coagulation, diagnostic criteria and treatment. Conclusion: Improvement was observed in the mortality of patients treated with anticoagulants such as protein C and antithrombin, among others. However, these findings have not achieved the relevance required to be recommended for inclusion in the treatment guides for disseminated intravascular coagulation.

    Título traducido de la contribuciónDisseminated intravascular coagulation and sepsis: Treatment and diagnostic criteria
    Idioma originalPortugués
    Número de artículoe1214
    PublicaciónRevista Cubana de Hematologia, Inmunologia y Hemoterapia
    EstadoPublicada - 2020

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