Criterios diagnósticos en 400 biopsias de adenocarcinoma de próstata

Alejandro Vélez Hoyos, José Jaime Correa, María Raquel Hessén, Carlos Humberto Martínez, Carlos Alberto Uribe, Camilo Pérez, Federico Escobar

    Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva


    Objective: To analyze a number of prostate biopsies evaluated by the same pathologist, to find the frequency of minimal histological criteria for prostate cancer and the new changes in the consensus of urologists in the Gleason classification. Materials and Methods: A total of 400 ultrasound-guided biopsies performed using a number 18 needle, and with the hematoxylin-eosin stained sections being evaluated by the same pathologist. Results: The histological characteristics in neoplastic glands were stromal infiltration (100%), no basal layer (100%), prominent nucleoli (98%), multiple nucleoli (60%), intraluminal crystalloids (40%), intraluminal amorphous eosinophilic material (70%), collagen micro nodules (1%), glomeruloid structures (10%), perineural invasion (20%), stromal retraction (32%) and invasion of fat (1%). Other associated histological findings were observed, such as atrophy, basal cell hyperplasia, atypical small acinar proliferation. Finally, was the assessment of the Gleason grading was assessed according to the new consensus of urologists seeing an increase in the number of cases with Gleason 7. Conclusions: The histological diagnosis of prostate cancer based on this study show that the most common criteria are stromal infiltration, absence of basement membrane and prominent nucleoli. Pathologists should be aware, and become familiar with this classification, as well as the changes that have been made over time.

    Título traducido de la contribuciónDiagnostic criteria in adenocarcinoma in 400 prostate biopsies using the new Gleason classification
    Idioma originalEspañol
    Páginas (desde-hasta)35-38
    Número de páginas4
    PublicaciónUrologia Colombiana
    EstadoPublicada - 1 abr. 2014

    Nota bibliográfica

    Publisher Copyright:
    © 2014 Sociedad Colombiana de Urología.

    Palabras clave

    • Biopsy
    • Prostate cancer


    Profundice en los temas de investigación de 'Criterios diagnósticos en 400 biopsias de adenocarcinoma de próstata'. En conjunto forman una huella única.

    Citar esto