Eritropoyesis ineficaz y su afección en la funcionalidad de la médula ósea en niños

Aplastic anemia has long been considered a rare blood disorder, with potentially fatal consequences if left untreated. It is characterized by the failure of bone marrow function of autoimmune origin. Such instances of functional insufficiency are often linked to viral infections, environmental toxins, as well as both inherited and acquired genetic mutations. Consequently, these disruptions lead to abnormal blood counts, resulting in decreased physical capacity and hindrance to the patient's daily activities, particularly prevalent among the pediatric population. The mainstay treatments for this condition include hematopoietic stem cell transplantation and immunosuppressive therapy. These interventions significantly enhance both the quality of life and the survival rates of affected individuals. However,
despite ongoing research efforts, alternative treatments with comparable or superior efficacy to the aforementioned methods remain elusive.