Esferocitosis hereditaria en neonatos y su fisiopatología: un enfoque molecular

Hereditary spherocytosis is a cause of hemolytic anemia that commonly affects neonates and infants; where hemolysis occurs due to the spheroidal shape, rigidity and fragility of erythrocytes in peripheral blood. These morphological changes are generated by genetic, protein and external factors to the erythrocyte membrane, which translates into the presence of clinical manifestations of the disease, which if it does not receive a timely diagnosis and early treatment can be responsible for mild to severe complications and even death.