Genetic make up and structure of Colombian populations by means of uniparental and biparental DNA markers

Winston Rojas, María Victoria Parra, Omer Campo, María Antonieta Caro, Juan Guillermo Lopera, William Arias, Constanza Duque, Andrés Naranjo, Jharley García, Candelaria Vergara, Jaime Lopera, Erick Hernandez, Ana Valencia, Yuri Caicedo, Mauricio Cuartas, Javier Gutiérrez, Sergio López, Andrés Ruiz-Linares, Gabriel Bedoya

Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva

120 Citas (Scopus)

Resumen

Colombia is a country with great geographic heterogeneity and marked regional differences in pre-Columbian native population density and in the extent of past African and European immigration. As a result, Colombia has one of the most diverse populations in Latin America. Here we evaluated ancestry in over 1,700 individuals from 24 Colombian populations using biparental (autosomal and X-Chromosome), maternal (mtDNA), and paternal (Y-chromosome) markers. Autosomal ancestry varies markedly both within and between regions, confirming the great genetic diversity of the Colombian population. The X-chromosome, mtDNA, and Y-chromosome data indicate that there is a pattern across regions indicative of admixture involving predominantly Native American women and European and African men.

Idioma originalInglés
Páginas (desde-hasta)13-20
Número de páginas8
PublicaciónAmerican Journal of Physical Anthropology
Volumen143
N.º1
DOI
EstadoPublicada - sep. 2010
Publicado de forma externa

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