Genome microsatellite diversity within the Apicomplexa phylum

Juan Pablo Isaza, Juan Fernando Alzate

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The Apicomplexa phylum groups include unicellular and obligate intracellular protozoan parasites with an apical complex used for attachment and invasion to host cells. In this study, we analyze single sequence repeats (SSRs) in the whole genome of 20 apicomplexan organisms that represent four different lineages within the phylum. Only perfect SSRs with at least 12 nucleotides and composed of 2–6 mers were included. To better understand the association of SSR types with the genomic regions, the SSRs were classified accordingly with the genomic location into exon, intron and intergenic categories. Our results showed heterogeneous SSRs density within the studied genomes. However, the most frequent SSRs types were di- and tri-nucleotide repeats. The former was associated with intergenic regions, while the latter was associated with exon regions.

Idioma originalInglés
Páginas (desde-hasta)2117-2129
Número de páginas13
PublicaciónMolecular Genetics and Genomics
EstadoPublicada - 1 dic. 2016
Publicado de forma externa

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Publisher Copyright:
© 2016, Springer-Verlag Berlin Heidelberg.


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