Genotoxicity of organic material extracted from particulate matter of alternative fuels

Valentina Nieto Marín, Leidy Vanessa Echavarría Mazo, Maritza Londoño Berrio, Luz Yaneth Orozco Jiménez, Verónica Estrada Vélez, Juan Pablo Isaza, Isabel Cristina Ortiz-Trujillo

    Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva

    2 Citas (Scopus)


    Global demand for energy is rapidly increasing, and resources for the production of petroleum-based fuels are running out. For this, renewable fuels like biodiesel and hydrotreated vegetable oil biofuel are considered important alternatives to replace such fuels. In this study, we evaluated the in vitro genotoxicity effect on HepG2 cells of organic material extracted from particulate matter emissions of an engine fueled with conventional diesel or mixtures of diesel with 10% of biomass. The emissions were collected in two operational modes, 2410 rpm (slope simulation) and 1890 rpm (plane). Genotoxicity was evaluated through two methods, chromosomal aberration test and the alkaline comet assay. The former did not show any genotoxic effect, but the latter exhibited a statistically significant effect despite the operational mode of the engine and the concentration organic material extracted. In conclusion, regardless of the concentration of organic material extracted from particulate matter, the operational mode of the engine, or the fuel used, a significant damage of the DNA was found. In general, at the physicochemical level, a decrease in the amount of emissions of the used fuels is not directly related to a decrease in the genotoxicity potential.

    Idioma originalInglés
    Páginas (desde-hasta)17844-17852
    Número de páginas9
    PublicaciónEnvironmental Science and Pollution Research
    EstadoPublicada - abr. 2021

    Nota bibliográfica

    Publisher Copyright:
    © 2021, Springer-Verlag GmbH Germany, part of Springer Nature.

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    • Artículos de investigación con calidad A1 / Q1


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