Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.
|Título traducido de la contribución||MicroRNAs: molecular biology as a tool for preeclampsia prediction|
|Número de artículo||100740|
|Publicación||Clinica e Investigacion en Ginecologia y Obstetricia|
|Estado||Publicada - 1 abr. 2022|
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- Molecular biology