MicroARN: la biología molecular como herramienta de predicción en preeclampsia

E. Sánchez Díaz; L. M. Martínez-Sánchez; M. D. Roldan Tabares; L. I. Jaramillo Jaramillo

doi:10.1016/j.gine.2021.100740

MicroARN: la biología molecular como herramienta de predicción en preeclampsia

E. Sánchez Díaz, L. M. Martínez-Sánchez, M. D. Roldan Tabares, L. I. Jaramillo Jaramillo

Resultado de la investigación: Contribución a una revista › Artículo de revisión › revisión exhaustiva

Resumen

Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.

Título traducido de la contribución	MicroRNAs: molecular biology as a tool for preeclampsia prediction
Idioma original	Español
Número de artículo	100740
Publicación	Clinica e Investigacion en Ginecologia y Obstetricia
Volumen	49
N.º	2
DOI	https://doi.org/10.1016/j.gine.2021.100740
Estado	Publicada - 1 abr. 2022

Nota bibliográfica

Publisher Copyright:
© 2021 Elsevier España, S.L.U.

Palabras clave

Hypertension
Molecular biology
Preeclampsia

Acceder al documento

10.1016/j.gine.2021.100740

Citar esto

@article{5ef1c514b5d44312a2584904fec3ab6d,

title = "MicroARN: la biolog{\'i}a molecular como herramienta de predicci{\'o}n en preeclampsia",

abstract = "Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.",

keywords = "Hypertension, Molecular biology, Preeclampsia",

author = "{S{\'a}nchez D{\'i}az}, E. and Mart{\'i}nez-S{\'a}nchez, {L. M.} and {Roldan Tabares}, {M. D.} and {Jaramillo Jaramillo}, {L. I.}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Espa{\~n}a, S.L.U.",

year = "2022",

month = apr,

day = "1",

doi = "10.1016/j.gine.2021.100740",

language = "Espa{\~n}ol",

volume = "49",

journal = "Clinica e Investigacion en Ginecologia y Obstetricia",

issn = "0210-573X",

publisher = "Ediciones Doyma, S.L.",

number = "2",

}

TY - JOUR

T1 - MicroARN

T2 - la biología molecular como herramienta de predicción en preeclampsia

AU - Sánchez Díaz, E.

AU - Martínez-Sánchez, L. M.

AU - Roldan Tabares, M. D.

AU - Jaramillo Jaramillo, L. I.

PY - 2022/4/1

Y1 - 2022/4/1

N2 - Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.

AB - Preeclampsia is a disease with a significant incidence worldwide that is directly associated with 15% of maternal deaths. This is usually characterized by the presence of hypertension and proteinuria, which manifests itself from the middle of pregnancy. MicroRNAs are single-stranded RNA molecules that act primarily by degrading transcribed messenger RNA or inhibiting microRNA translation. Placental microRNAs play a role in the growth and function of the placenta, their potential use as diagnostic biomarkers is considered feasible due to the ability to enter the maternal circulation and be detectable in maternal plasma.

KW - Hypertension

KW - Molecular biology

KW - Preeclampsia

UR - http://www.scopus.com/inward/record.url?scp=85123007359&partnerID=8YFLogxK

U2 - 10.1016/j.gine.2021.100740

DO - 10.1016/j.gine.2021.100740

M3 - Artículo de revisión

AN - SCOPUS:85123007359

SN - 0210-573X

VL - 49

JO - Clinica e Investigacion en Ginecologia y Obstetricia

JF - Clinica e Investigacion en Ginecologia y Obstetricia

IS - 2

M1 - 100740

ER -

MicroARN: la biología molecular como herramienta de predicción en preeclampsia

Resumen

Nota bibliográfica

Palabras clave

Acceder al documento

Huella

Citar esto