Outcome of reintubated patients after scheduled extubation

Fernando Frutos-Vivar, Andrés Esteban, Carlos Apezteguia, Marco González, Yaseen Arabi, Marcos I. Restrepo, Federico Gordo, Cristina Santos, Jamal A. Alhashemi, Fernando Pérez, Oscar Peñuelas, Antonio Anzueto

    Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

    146 Citas (Scopus)

    Resumen

    Purpose: The main objective of study was to evaluate the outcome of patients who require reintubation after elective extubation. Materials and Methods: This is an observational, prospective cohort study including mechanically ventilated patients who passed successfully a spontaneous breathing trial. Patients were observed for 48 hours after extubation. During this time, reintubation or use of noninvasive positive pressure ventilation was considered as a failure. Reintubated patients were followed after the reintubation to register complications and outcome. Results: A total of 1,152 extubated patients were included in the analysis. Three hundred thirty-six patients (29%) met the criteria for extubation failure. Extubation failure was independently associated with mortality (odds ratio, 3.29; 95% confidence interval, 2.19-4.93). One hundred eighty patients (16% of overall cohort) required reintubation within 48 hours after extubation. Median time from extubation to reintubation was 13 hours (interquartile range, 6-24 hours). Reintubation was independently associated with mortality (odds ratio, 5.18; 95% confidence interval, 3.38-7.94; P < .001). Higher mortality of reintubated patients was due to the development of complications after the reintubation. Conclusions: In a large cohort of scheduled extubated patients, one third of patients developed extubation failure, of whom half needed reintubation. Reintubation was associated with increased mortality due to the development of new complications after reintubation.

    Idioma originalInglés
    Páginas (desde-hasta)502-509
    Número de páginas8
    PublicaciónJournal of Critical Care
    Volumen26
    N.º5
    DOI
    EstadoPublicada - oct. 2011

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