Perfil clínico y epidemiológico de los pacientes con enfermedad hemolítica del recién nacido atendidos en un hospital universitario, Medellín, Colombia, 2014-2018

Mariana Roldán-Isaza, Daniela Vergara-Yánez, Alejandro Hernández-Martínez, Natalia Morales-Quintero, María de los Ángeles Rodríguez-Gázquez, Lina María Martínez-Sánchez

    Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva

    Resumen

    BACKGROUND: Hemolytic disease of the newborn (HDN) refers to the perinatal effects of fetal maternal erythrocyte isoimmunization that leads to an immune reaction allowing lysis of these cells. OBJECTIVE: To describe the clinical and epidemiological profile of patients with HDN treated in a university hospital during the 2014-2018 period. Materials and methods: Observational, descriptive, retrospective, cross-sectional study that included neonates with EHRN and their mothers. A non-probabilistic sampling of consecutive cases was carried out. RESULTS: 216 newborns diagnosed with HDN were included, with a mean gestational age of 38.1±2.18 weeks. Blood group A predominated in the neonate with 62.5% and group O in the mother with 88.4%. Regarding the clinical presentation, 85.1% of the patients presented jaundice, 86.4% received phototherapy and only 1.4% had complications. CONCLUSION: The HDN in this study shows jaundice as the most frequent sign, allowing a diagnosis generally in the first 48 hours postpartum and an effective and timely intervention. It was identified that a large part of the population required phototherapy and red blood cell transfusions for their treatment to avoid later complications.

    Título traducido de la contribuciónClinical and epidemiological profile of patients with hemolytic anemia of the newborn treated in a university hospital, Medellin, Colombia, 2014-2018
    Idioma originalEspañol
    Páginas (desde-hasta)109-119
    Número de páginas11
    PublicaciónActa Pediatrica de Mexico
    Volumen44
    N.º2
    DOI
    EstadoPublicada - 2023

    Nota bibliográfica

    Publisher Copyright:
    © 2023 Instituto Nacional de Pediatria. All rights reserved.

    Palabras clave

    • Anemia, Hemolytic
    • Erythroblastosis, Fetal
    • Hydrops Fetalis
    • Infant, Newborn
    • Rh Isoimmunization

    Tipos de Productos Minciencias

    • Artículos de investigación con calidad Q4

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