Pulmonary compromise in inpatients with human immunodeficiency virus infection at Pablo Tobón Uribe Hospital, Medellín, Colombia

Título traducido de la contribución: Compromiso pulmonar en pacientes hospitalizados con infección por el virus de inmunodeficiencia humana en el Hospital Pablo Tobón Uribe (Medellín, Colombia)

Franco E. Montúfar-Andrade, Juan P. Villa-Franco, María Camila Montúfar-Pantoja, Juan C. Cadavid-Usuga, María A. Monsalve, Mateo Zuluaga, Laura Díaz, Juliana Vega, Juan D. Vélez, John J. Zuleta-Tobón, Camilo Madrid

    Producción científica: Contribución a una revistaArtículo en revista científica indexadarevisión exhaustiva

    4 Citas (Scopus)

    Resumen

    More than a half of patients with HIV infection have pulmonary involvement throughout their lives. Opportunistic infections are the main cause; however, many patients have noninfectious pulmonary involvement. Objective To describe the characteristics of pulmonary involvement in inpatients with HIV infection. Methods Descriptive observational study. Results A total of 63 patients were included, and 85.7% were men. The average age was 40.6 ± 12 years. Some 21.4% had a history of sexual promiscuity and 28.6% were men who had sex with men. Smoking was found in 60.3%, alcoholism in 52.4% and drug abuse in 20.6%. A tuberculosis history was documented in 23.8% of patients. At admission, 79.4% had AIDS, the mean CD4 count was 138.5 ± 17.7 cells/mm3 and 49.2% had CD4 counts < 100 cells/mm3. Major comorbidities included neoplastic disease in 20.6%, chronic diarrhea in 19%, COPD in 6.3% and diabetes in 3.2%. Major opportunistic agents were Mycobacterium spp, H. capsulatum and P. jirovecii. Kaposi's sarcoma, lymphoproliferative disease and COPD were causes of noninfectious pulmonary involvement. The main radiographic findings included interstitial infiltrates in 42.9%, pleural involvement in 23.8%, alveolar infiltrates in 7.9% and cavitary lesions in 7.9%. Multilobar compromise was evident in 15.9% of the patients. The major complications were respiratory failure, multiple organ dysfunction and acute renal failure. Some 19% required care in the ICU and 83.3% of these required mechanical ventilation. The mean stay was 18 ± 20 days and the mortality was 17.5%. Discussion Opportunistic infections are the main causes of lung involvement and mycobacterial diseases were most frequent. Mycobacterial diseases can occur simultaneously with an opportunistic infection, but in our series this was infrequent. Non-infectious diseases are important but are less common.

    Título traducido de la contribuciónCompromiso pulmonar en pacientes hospitalizados con infección por el virus de inmunodeficiencia humana en el Hospital Pablo Tobón Uribe (Medellín, Colombia)
    Idioma originalInglés
    Páginas (desde-hasta)211-217
    Número de páginas7
    PublicaciónInfectio
    Volumen20
    N.º4
    DOI
    EstadoPublicada - 1 oct. 2016

    Nota bibliográfica

    Publisher Copyright:
    © 2015 ACIN

    Huella

    Profundice en los temas de investigación de 'Compromiso pulmonar en pacientes hospitalizados con infección por el virus de inmunodeficiencia humana en el Hospital Pablo Tobón Uribe (Medellín, Colombia)'. En conjunto forman una huella única.

    Citar esto