Reversión de anticoagulantes orales directos: una perspectiva desde Urgencias

Introduction. Bleeding in the context of anticoagulation is one of the risks faced by some patients during certain treatments, and is potentially deadly. It is important to be aware of the pharmacokinetics of these molecules in order to predict their behavior. Clinical judgment is also required in all cases of bleeding, because management will depend on its severity. The purpose of this review is to present an approach to an anticoagulated patient with bleeding in the emergency ward. Topics Discussed. Pharmacokinetics and pharmacodynamics, generalities, major and non-major bleeding, reversal options and treatment. Conclusion. If direct oral anticoagulants (DOACS) are present, it is necessary to assess the severity of bleeding and the degree of anticoagulation because the management treatment depends on whether bleeding is major or minor.