Spontaneous pneumomediastinum: An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases

Pablo Arango Guerra; Santiago Monsalve Yepes; Andrés Chavarriaga Restrepo; Carlos Jaime Velasquez Franco

doi:10.1016/j.reuma.2023.12.002

Spontaneous pneumomediastinum: An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases

Título traducido de la contribución: Neumomediastino espontáneo: una manifestación extramuscular de la dermatomiositis anti-MDA5. Reporte de 2 casos

Pablo Arango Guerra, Santiago Monsalve Yepes, Andrés Chavarriaga Restrepo, Carlos Jaime Velasquez Franco

Producción científica: Contribución a una revista › Artículo en revista científica indexada › revisión exhaustiva

1 Cita (Scopus)

Resumen

The use of specific antibodies in inflammatory myopathies has improved the characterization of this disease, identifying different clinical phenotypes. Patients with dermatomyositis and anti-MDA5 antibodies display typical skin symptoms, lesser muscular involvement, and a prevalence of interstitial lung disease of up to 91%. Beyond interstitial lung disease, spontaneous pneumomediastinum has been identified as a rare but potentially fatal pulmonary manifestation. Two cases of this complication in patients with anti-MDA5 dermatomyositis are reported.

Título traducido de la contribución	Neumomediastino espontáneo: una manifestación extramuscular de la dermatomiositis anti-MDA5. Reporte de 2 casos
Idioma original	Inglés
Páginas (desde-hasta)	218-222
Número de páginas	5
Publicación	Reumatologia Clinica
Volumen	20
N.º	4
DOI	https://doi.org/10.1016/j.reuma.2023.12.002
Estado	Publicada - abr. 2024
Publicado de forma externa	Sí

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Publisher Copyright:
© 2023 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología

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title = "Spontaneous pneumomediastinum: An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases",

abstract = "The use of specific antibodies in inflammatory myopathies has improved the characterization of this disease, identifying different clinical phenotypes. Patients with dermatomyositis and anti-MDA5 antibodies display typical skin symptoms, lesser muscular involvement, and a prevalence of interstitial lung disease of up to 91%. Beyond interstitial lung disease, spontaneous pneumomediastinum has been identified as a rare but potentially fatal pulmonary manifestation. Two cases of this complication in patients with anti-MDA5 dermatomyositis are reported.",

keywords = "Dermatomyositis, Interstitial lung disease, Pneumomediastinum, Pneumothorax, Subcutaneous emphysema",

author = "{Arango Guerra}, Pablo and {Monsalve Yepes}, Santiago and {Chavarriaga Restrepo}, Andr{\'e}s and {Velasquez Franco}, {Carlos Jaime}",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier Espa{\~n}a, S.L.U. and Sociedad Espa{\~n}ola de Reumatolog{\'i}a y Colegio Mexicano de Reumatolog{\'i}a",

year = "2024",

month = apr,

doi = "10.1016/j.reuma.2023.12.002",

language = "Ingl{\'e}s",

volume = "20",

pages = "218--222",

journal = "Reumatologia Clinica",

issn = "1699-258X",

publisher = "Ediciones Doyma, S.L.",

number = "4",

}

Spontaneous pneumomediastinum: An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases. / Arango Guerra, Pablo; Monsalve Yepes, Santiago; Chavarriaga Restrepo, Andrés et al.
En: Reumatologia Clinica, Vol. 20, N.º 4, 04.2024, p. 218-222.

Producción científica: Contribución a una revista › Artículo en revista científica indexada › revisión exhaustiva

TY - JOUR

T1 - Spontaneous pneumomediastinum

T2 - An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases

AU - Arango Guerra, Pablo

AU - Monsalve Yepes, Santiago

AU - Chavarriaga Restrepo, Andrés

AU - Velasquez Franco, Carlos Jaime

PY - 2024/4

Y1 - 2024/4

N2 - The use of specific antibodies in inflammatory myopathies has improved the characterization of this disease, identifying different clinical phenotypes. Patients with dermatomyositis and anti-MDA5 antibodies display typical skin symptoms, lesser muscular involvement, and a prevalence of interstitial lung disease of up to 91%. Beyond interstitial lung disease, spontaneous pneumomediastinum has been identified as a rare but potentially fatal pulmonary manifestation. Two cases of this complication in patients with anti-MDA5 dermatomyositis are reported.

AB - The use of specific antibodies in inflammatory myopathies has improved the characterization of this disease, identifying different clinical phenotypes. Patients with dermatomyositis and anti-MDA5 antibodies display typical skin symptoms, lesser muscular involvement, and a prevalence of interstitial lung disease of up to 91%. Beyond interstitial lung disease, spontaneous pneumomediastinum has been identified as a rare but potentially fatal pulmonary manifestation. Two cases of this complication in patients with anti-MDA5 dermatomyositis are reported.

KW - Dermatomyositis

KW - Interstitial lung disease

KW - Pneumomediastinum

KW - Pneumothorax

KW - Subcutaneous emphysema

UR - http://www.scopus.com/inward/record.url?scp=85182381758&partnerID=8YFLogxK

U2 - 10.1016/j.reuma.2023.12.002

DO - 10.1016/j.reuma.2023.12.002

M3 - Artículo en revista científica indexada

AN - SCOPUS:85182381758

SN - 1699-258X

VL - 20

SP - 218

EP - 222

JO - Reumatologia Clinica

JF - Reumatologia Clinica

IS - 4

ER -

Spontaneous pneumomediastinum: An extra muscular manifestation of anti-MDA5 dermatomyositis. Report of 2 cases

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