Tumor fibroso solitario de próstata: informe de caso y revisión de la literatura

Alejandro Cardona-Palacio, Alejandro Vélez-Hoyos, María Angélica Mendoza-Rodríguez

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    Resumen

    Solitary fibrous tumor (SFT) is a mesenchymal neoplasm of fibroblastic type, which despite being located mainly in the pleura, has been observed in other organs such as the prostate. On the other hand, solitary fibrous tumor of the prostate is a rare neoplasm, slow growing, and of uncertain malignant potential, which is generally composed of spindle cells of cytologically benign appearance, arranged in a disorganized architecture, mixed with collagen and small blood vessels. Es-tablishing its diagnosis has become more reproducible since the identification of the NAB2-STAT6 gene fusion by molecular biology, leading to the overexpression of STAT6 by immunohistochemistry, a very sensitive and specific marker for SFT. We present a clinical report of a patient who consulted with symptoms of bladder compression, in whom a mass was identified with the epicenter in the prostate infiltrating into the bladder and reaching the rectal wall. Following histopathology study, immunohistochemistry and molecular tests it was classified as a SFT of the prostate, finally treated with radical cystoprostatectomy plus urinary shunt.

    Título traducido de la contribuciónSolitary fibrous tumor of the prostate: case report and literature review
    Idioma originalEspañol
    Páginas (desde-hasta)131-138
    Número de páginas8
    PublicaciónMedicina y Laboratorio
    Volumen27
    N.º2
    DOI
    EstadoPublicada - 1 abr. 2023

    Nota bibliográfica

    Publisher Copyright:
    © 2023, Universidad de Antioquia. All rights reserved.

    Palabras clave

    • STAT6 transcrip-tion factor
    • prostate
    • prostatectomy
    • prostatic neoplasms
    • solitary fibrous tumor

    Tipos de Productos Minciencias

    • Artículos de investigación con calidad Q4

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